› 6rus

X-ray diffraction
2.8Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151102 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Properdin Chain: A
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 25.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P27918 (Residues: 28-255; Coverage: 52%)
Gene names: CFP, PFC
Sequence domains:
Properdin Chain: B
Molecule details ›
Chain: B
Length: 221 amino acids
Theoretical weight: 24.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P27918 (Residues: 256-469; Coverage: 48%)
Gene names: CFP, PFC
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: FUC, BGC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: FUC, NAG
Carbohydrate polymer
2 bound ligands:
Ligand MAN 15 x MAN
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: C2
Unit cell:
a: 183.97Å b: 47.11Å c: 122.93Å
α: 90° β: 119.41° γ: 90°
R-values:
R R work R free
0.241 0.238 0.274
Expression system: Homo sapiens

Quick links

Citations

5 review citations

Complement component C3: A structural perspective and potential therapeutic implications.
Geisbrecht et al. (2022)
4 more

4 mentions without citation

Meta-heterogeneity: Evaluating and Describing the Diversity in Glycosylation Between Sites on the Same Glycoprotein.
Čaval et al. (2021)
3 more