› 6t5l

X-ray diffraction
2.17Å resolution

MYO-1 from Myroides odoratimimus. Environmental metallo-beta-lactamases exhibit high enzymatic activity under zinc deprivation

Released:
DOI: 10.2210/pdb6t5l/pdb
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PDB entry 6t5l coloured by chain, front view.
PDB entry 6t5l coloured by chain, side view.
PDB entry 6t5l coloured by chain, top view.
Source organism: Myroides odoratimimus
Primary publication:
Structural and biochemical characterization of the environmental MBLs MYO-1, ECV-1 and SHD-1.
Fröhlich C, Sørum V, Huber S, Samuelsen Ø, Berglund F, Kristiansson E, Kotsakis SD, Marathe NP, Larsson DGJ, Leiros HS
OpenAccess logo J Antimicrob Chemother 75 2554-2563 (2020)
PMID: 32464640

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-244840 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Subclass B1 metallo-beta-lactamase Chains: A, B
Molecule details ›
Chains: A, B
Length: 238 amino acids
Theoretical weight: 26.82 KDa
Source organism: Myroides odoratimimus
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
Ligand ZN 4 x ZN
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-3
Spacegroup: P65
Unit cell:
a: 144.684Å b: 144.684Å c: 53.306Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.219 0.217 0.253
Expression system: Escherichia coli

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Citations

1 review citation

Comparative genomic assessment of members of genus Tenacibaculum: an exploratory study.
Satyam et al. (2023)
3 other articles

2 mentions without citation

Structural and biochemical characterization of the environmental MBLs MYO-1, ECV-1 and SHD-1.
Fröhlich et al. (2020)
1 more

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