› 6tr9

X-ray diffraction
2.46Å resolution

Crystal structure of human L ferritin (HuLf) triple variant E60A-E61A-E64A

Released:
DOI: 10.2210/pdb6tr9/pdb
PDB entry 6tr9 coloured by chain, front view.
PDB entry 6tr9 coloured by chain, side view.
PDB entry 6tr9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Ciambellotti S, Pozzi C, Mangani S, Turano P
Chemistry 26 5770-5773 (2020)
PMID: 32027764

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136239 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin light chain Chain: AAA
Molecule details ›
Chain: AAA
Length: 175 amino acids
Theoretical weight: 19.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P02792 (Residues: 1-175; Coverage: 100%)
Gene name: FTL
Sequence domains: Ferritin-like domain

Ligands and Environments

1 bound ligand:
Ligand CD 7 x CD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: I432
Unit cell:
a: 151.215Å b: 151.215Å c: 151.215Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.2 0.258
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

Advances in Ferritin Physiology and Possible Implications in Bacterial Infection.
Gehrer et al. (2023)
5 other articles