› 6up6

Electron Microscopy
9Å resolution

Endophilin B1 helical scaffold

Released:
DOI: 10.2210/pdb6up6/pdb
PDB entry 6up6 coloured by chain, front view.
PDB entry 6up6 coloured by chain, side view.
PDB entry 6up6 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Amphipathic Motifs Regulate N-BAR Protein Endophilin B1 Auto-inhibition and Drive Membrane Remodeling.
Bhatt VS, Ashley R, Sundborger-Lunna A
Structure 29 61-69.e3 (2021)
PMID: 33086035
Related structures: EMD-20835

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 44-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195183 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endophilin-B1 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V, W, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, v, w
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V, W, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, v, w
Length: 365 amino acids
Theoretical weight: 40.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y371 (Residues: 1-365; Coverage: 100%)
Gene names: CGI-61, KIAA0491, SH3GLB1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 9Å
Relevant EMDB volumes: EMD-20835
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Activation Mechanisms of the VPS34 Complexes.
Ohashi Y. (2021)
1 more