› 6usm

X-ray diffraction
3.37Å resolution

Structure of nuclease domain of human parvovirus B19 non-structural protein 1 in complex with zinc

Released:
DOI: 10.2210/pdb6usm/pdb
PDB entry 6usm coloured by chain, front view.
PDB entry 6usm coloured by chain, side view.
PDB entry 6usm coloured by chain, top view.
Source organisms:
Entry author: Tewary SK

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142629 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Maltose/maltodextrin-binding periplasmic protein Chain: A
Molecule details ›
Chain: A
Length: 371 amino acids
Theoretical weight: 40.81 KDa
Source organism: Escherichia coli
Expression system: Expression vector pET-mod
UniProt:
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
Gene names: JW3994, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein
Non-structural protein NS1 Chain: B
Molecule details ›
Chain: B
Length: 171 amino acids
Theoretical weight: 19.48 KDa
Source organism: Human parvovirus B19
Expression system: Expression vector pET-mod
UniProt:
  • Canonical: Q6TV13 (Residues: 1-171; Coverage: 26%)
Gene name: NS
Sequence domains: Rep protein catalytic domain like

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
Carbohydrate polymer
1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P3121
Unit cell:
a: 102.69Å b: 102.69Å c: 134.21Å
α: 90° β: 90° γ: 120°
Expression system: Expression vector pET-mod

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