› 6vye

X-ray diffraction
1.95Å resolution

6-phosphogluconolactonase from Trypanosoma cruzi

Released:
DOI: 10.2210/pdb6vye/pdb
Model geometry
Data not analysed
Fit model/data
Data not analysed
PDB entry 6vye coloured by chain, front view.
PDB entry 6vye coloured by chain, side view.
PDB entry 6vye coloured by chain, top view.
Source organism: Trypanosoma cruzi strain CL Brener
Entry authors: Merritt EA, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Reaction catalysed: 
6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175450 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6-phosphogluconolactonase Chains: A, B
Molecule details ›
Chains: A, B
Length: 271 amino acids
Theoretical weight: 29.71 KDa
Source organism: Trypanosoma cruzi strain CL Brener
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4CQA8 (Residues: 1-263; Coverage: 100%)
Gene name: Tc00.1047053503945.40
Sequence domains: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase

Ligands and Environments

2 bound ligands:
Ligand PO4 3 x PO4
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P2
Unit cell:
a: 71.77Å b: 63.39Å c: 79.32Å
α: 90° β: 94.91° γ: 90°
R-values:
R R work R free
0.233 0.231 0.27
Expression system: Escherichia coli

Quick links

PDB-REDO

The sliders below show the change in model quality between original PDB entry and the PDB-REDO entry

Model Geometry
 
 
Data not available
DNA/RNA Geometry
 
 
Data not available
Fit model/data
 
 
Data not available
PDB-REDO