6w2x

Electron Microscopy
3.6Å resolution

CryoEM Structure of Inactive GABAB Heterodimer

Released:
Source organism: Homo sapiens
Related structures: EMD-21533

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-131164 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Gamma-aminobutyric acid type B receptor subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 829 amino acids
Theoretical weight: 94.17 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9UBS5 (Residues: 153-961; Coverage: 86%)
  • Best match: Q9UBS5-2 (Residues: 30-844)
Gene names: GABBR1, GPRC3A
Sequence domains:
Gamma-aminobutyric acid type B receptor subunit 2 Chain: B
Molecule details ›
Chain: B
Length: 908 amino acids
Theoretical weight: 102.8 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O75899 (Residues: 42-941; Coverage: 100%)
Gene names: GABBR2, GPR51, GPRC3B
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-21533
Expression system: Spodoptera frugiperda