› 6wzq

X-ray diffraction
1.45Å resolution

Structure of SARS-CoV-2 Nucleocapsid dimerization domain, P21 form

Released:
DOI: 10.2210/pdb6wzq/pdb
PDB entry 6wzq coloured by chain, front view.
PDB entry 6wzq coloured by chain, side view.
PDB entry 6wzq coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein.
Ye Q, West AMV, Silletti S, Corbett KD
OpenAccess logo Protein Sci 29 1890-1901 (2020)
PMID: 32654247

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145015 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 137 amino acids
Theoretical weight: 15.59 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DTC9 (Residues: 247-364; Coverage: 28%)
Gene name: N
Sequence domains: Coronavirus nucleocapsid

Ligands and Environments

1 bound ligand:
Ligand SO4 6 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 71.146Å b: 43.546Å c: 74.233Å
α: 90° β: 94.87° γ: 90°
R-values:
R R work R free
0.168 0.167 0.18
Expression system: Escherichia coli

Quick links

Citations

37 review citations

Structural insights into SARS-CoV-2 proteins.
Arya et al. (2021)
36 more

17 mentions without citation

A Comprehensive Review about the Molecular Structure of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Insights into Natural Products against COVID-19.
Saied et al. (2021)
16 more