› 6xmp

Electron Microscopy
3.5Å resolution

Structure of P5A-ATPase Spf1, Apo form

Released:
DOI: 10.2210/pdb6xmp/pdb
PDB entry 6xmp coloured by chain, front view.
PDB entry 6xmp coloured by chain, side view.
PDB entry 6xmp coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase.
McKenna MJ, Sim SI, Ordureau A, Wei L, Harper JW, Shao S, Park E
Science 369 (2020)
PMID: 32973005
Related structures: EMD-22260

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153990 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endoplasmic reticulum transmembrane helix translocase Chain: A
Molecule details ›
Chain: A
Length: 1239 amino acids
Theoretical weight: 137.57 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae BY4741
UniProt:
  • Canonical: P39986 (Residues: 1-1215; Coverage: 100%)
Gene names: COD1, SPF1, YEL031W
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand LMT 12 x LMT
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-22260
Expression system: Saccharomyces cerevisiae BY4741

Quick links

Citations

14 review citations

The mechanisms of integral membrane protein biogenesis.
Hegde et al. (2022)
13 more

2 mentions without citation

The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase.
McKenna et al. (2020)
1 more