› 6y62

X-ray diffraction
2.2Å resolution

Crystal structure of the envelope glycoprotein complex of Maporal virus in a prefusion conformation

Released:
DOI: 10.2210/pdb6y62/pdb
PDB entry 6y62 coloured by chain, front view.
PDB entry 6y62 coloured by chain, side view.
PDB entry 6y62 coloured by chain, top view.
Source organism: Maporal virus
Primary publication:
The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Serris A, Stass R, Bignon EA, Muena NA, Manuguerra JC, Jangra RK, Li S, Chandran K, Tischler ND, Huiskonen JT, Rey FA, Guardado-Calvo P
Cell 183 442-456.e16 (2020)
PMID: 32937107

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-561859 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Envelope glycoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 891 amino acids
Theoretical weight: 96.57 KDa
Source organism: Maporal virus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: Q5MYC0 (Residues: 22-374, 652-1107; Coverage: 71%)
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: C2
Unit cell:
a: 120.33Å b: 65.013Å c: 144.757Å
α: 90° β: 99.72° γ: 90°
R-values:
R R work R free
0.196 0.194 0.226
Expression system: Drosophila melanogaster

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Citations

11 review citations

Recent Advances in Bunyavirus Glycoprotein Research: Precursor Processing, Receptor Binding and Structure.
Hulswit et al. (2021)
10 more

4 mentions without citation

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Serris et al. (2020)
3 more