6z2q

X-ray diffraction
2.35Å resolution

Crystal structure of wild type OgpA from Akkermansia muciniphila in complex with an O-glycopeptide (GalGalNAc-TS) product

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-502552 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Peptidase M43 pregnancy-associated plasma-A domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 371 amino acids
Theoretical weight: 41.86 KDa
Source organism: Akkermansia muciniphila ATCC BAA-835
Expression system: Escherichia coli
UniProt:
  • Canonical: B2UR60 (Residues: 25-385; Coverage: 100%)
Gene name: Amuc_1119
Drosocin Chain: D
Molecule details ›
Chain: D
Length: 19 amino acids
Theoretical weight: 2.2 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P36193 (Residues: 22-40; Coverage: 42%)
Gene names: CG10816, Dro

Ligands and Environments

Carbohydrate polymer : NEW Components: A2G, GAL
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P41212
Unit cell:
a: 65.366Å b: 65.366Å c: 187.654Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.2 0.251
Expression systems:
  • Escherichia coli
  • Not provided