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Electron Microscopy
3.9Å resolution

The structure of CVA10 mature virion in complex with Fab 2G8

Released:

Function and Biology Details

Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero 360-mer (preferred)
PDBe Complex ID:
PDB-CPX-207390 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
VL of Fab 2G8 Chain: L
Molecule details ›
Chain: L
Length: 113 amino acids
Theoretical weight: 12.39 KDa
Source organism: Mus musculus
VH of Fab 2G8 Chain: H
Molecule details ›
Chain: H
Length: 115 amino acids
Theoretical weight: 13.15 KDa
Source organism: Mus musculus
VP1 Chain: A
VP2 Chain: B
VP3 Chain: C
VP4 Chain: D

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-9604