› 6aiy

X-ray diffraction
1.9Å resolution

Crystal structure of DXO (E234A mutant) in complex with adenosine 3', 5' bisphosphate and two magnesium ions

Released:
DOI: 10.2210/pdb6aiy/pdb
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PDB entry 6aiy coloured by chain, front view.
PDB entry 6aiy coloured by chain, side view.
PDB entry 6aiy coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate.
Yun JS, Yoon JH, Choi YJ, Son YJ, Kim S, Tong L, Chang JH
Biochem Biophys Res Commun 504 89-95 (2018)
PMID: 30180947

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130692 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Decapping and exoribonuclease protein Chain: A
Molecule details ›
Chain: A
Length: 378 amino acids
Theoretical weight: 43.07 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O70348 (Residues: 27-384; Coverage: 90%)
Gene names: Dom3z, Dxo, Ng6
Sequence domains: RAI1 like PD-(D/E)XK nuclease

Ligands and Environments

2 bound ligands:
Ligand A3P 1 x A3P
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21
Unit cell:
a: 46.499Å b: 88.081Å c: 50.04Å
α: 90° β: 114.42° γ: 90°
R-values:
R R work R free
0.172 0.17 0.203
Expression system: Escherichia coli

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Citations

1 review citation

The life and times of a tRNA.
Phizicky et al. (2023)
8 other articles

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