› 6aq1

X-ray diffraction
1.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138660 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, heart Chains: A, B
Molecule details ›
Chains: A, B
Length: 136 amino acids
Theoretical weight: 15.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05413 (Residues: 1-133; Coverage: 100%)
Gene names: FABP11, FABP3, MDGI
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand SO4 4 x SO4
Ligand PLM 2 x PLM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21
Unit cell:
a: 43.504Å b: 52.904Å c: 55.51Å
α: 90° β: 97.453° γ: 90°
R-values:
R R work R free
0.172 0.17 0.198
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structure-based molecular modeling in SAR analysis and lead optimization.
Temml et al. (2021)
13 other articles

5 mentions without citation

Fatty Acid Signaling Mechanisms in Neural Cells: Fatty Acid Receptors.
Falomir-Lockhart et al. (2019)
4 more