6asc

X-ray diffraction
2.15Å resolution

Mre11 dimer in complex with Endonuclease inhibitor PFM04

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-578468 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA double-strand break repair protein Mre11 Chains: A, B
Molecule details ›
Chains: A, B
Length: 336 amino acids
Theoretical weight: 38.58 KDa
Source organism: Thermotoga maritima MSB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X1X0 (Residues: 2-324; Coverage: 84%)
Gene names: TM_1635, mre11
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 12.3.1
Spacegroup: P21
Unit cell:
a: 48.053Å b: 112.682Å c: 81.162Å
α: 90° β: 100.26° γ: 90°
R-values:
R R work R free
0.198 0.197 0.232
Expression system: Escherichia coli