› 6b9k

Solution NMR

Solution NMR Structure of Unbound P18-I10

Released:
DOI: 10.2210/pdb6b9k/pdb
PDB entry 6b9k coloured by chain, ensemble of 20 models, front view.
PDB entry 6b9k coloured by chain, ensemble of 20 models, side view.
PDB entry 6b9k coloured by chain, ensemble of 20 models, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle.
McShan AC, Natarajan K, Kumirov VK, Flores-Solis D, Jiang J, Badstübner M, Toor JS, Bagshaw CR, Kovrigin EL, Margulies DH, Sgourakis NG
OpenAccess logo Nat Chem Biol 14 811-820 (2018)
PMID: 29988068

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137921 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Surface protein gp120 Chain: A
Molecule details ›
Chain: A
Length: 10 amino acids
Theoretical weight: 1.08 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P04578 (Residues: 311-320; Coverage: 1%)
Gene name: env

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 52%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21

Quick links

Citations

13 review citations

Peptide-Based Vaccines: Current Progress and Future Challenges.
Malonis et al. (2020)
12 more

1 mention without citation

Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle.
McShan et al. (2018)