› 6bbw

X-ray diffraction
1.8Å resolution

Structure of the major pilin protein (T3.2) from Streptococcus pyogenes serotype GAS13637

Released:
DOI: 10.2210/pdb6bbw/pdb
PDB entry 6bbw coloured by chain, front view.
PDB entry 6bbw coloured by chain, side view.
PDB entry 6bbw coloured by chain, top view.
Source organism: Streptococcus pyogenes
Primary publication:
Group A Streptococcus T Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design.
Young PG, Raynes JM, Loh JM, Proft T, Baker EN, Moreland NJ
Infect Immun 87 (2019)
PMID: 30936156

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-100728 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major pilin backbone protein T-antigen Chains: A, B
Molecule details ›
Chains: A, B
Length: 282 amino acids
Theoretical weight: 31.46 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A096ZHB0 (Residues: 1-282; Coverage: 98%)
Gene name: tee
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P1
Unit cell:
a: 32.05Å b: 60.57Å c: 72.79Å
α: 90.77° β: 91.77° γ: 104.07°
R-values:
R R work R free
0.2 0.198 0.249
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Genetics, Structure, and Function of Group A Streptococcal Pili.
Nakata et al. (2021)
4 other articles

1 mention without citation

Group A Streptococcus T Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design.
Young et al. (2019)