› 6bd9

X-ray diffraction
1.98Å resolution

Function and Biology Details

Reaction catalysed: 
2 pyruvate = 2-acetolactate + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139528 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetolactate synthase catalytic subunit, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 677 amino acids
Theoretical weight: 73.6 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P07342 (Residues: 58-687; Coverage: 92%)
Gene names: ILV2, SMR1, YM9718.07, YMR108W
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand TPP 2 x TPP

Cofactor: Ligand FAD 2 x FAD
5 bound ligands:
Ligand K 2 x K
Ligand MG 2 x MG
Ligand PYR 4 x PYR
Ligand OXY 8 x OXY
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P212121
Unit cell:
a: 96.024Å b: 110.967Å c: 180.244Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 0.159 0.181
Expression system: Escherichia coli

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