6c14

Electron Microscopy
4.5Å resolution

CryoEM structure of mouse PCDH15-1EC-LHFPL5 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-175631 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protocadherin-15 Chains: A, C
Molecule details ›
Chains: A, C
Length: 337 amino acids
Theoretical weight: 37.46 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q99PJ1 (Residues: 1144-1465; Coverage: 17%)
  • Best match: Q99PJ1-10 (Residues: 1151-1472)
Gene name: Pcdh15
Sequence domains: Cadherin domain
LHFPL tetraspan subfamily member 5 protein Chains: B, D
Molecule details ›
Chains: B, D
Length: 228 amino acids
Theoretical weight: 25.07 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q4KL25 (Residues: 1-219; Coverage: 100%)
Gene names: Lhfpl5, Tmhs
Sequence domains: Lipoma HMGIC fusion partner-like protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.5Å
Relevant EMDB volumes: EMD-7328
Expression system: Homo sapiens