Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- RNA polymerase sigma-70
- DNA-directed RNA polymerase, insert domain superfamily
- DNA-directed RNA polymerase, RpoA/D/Rpb3-type
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerase, alpha subunit
- DNA-directed RNA polymerase, omega subunit
- RNA polymerase, alpha subunit, C-terminal
- DNA-directed RNA polymerase, insert domain
38 more domains
Structure analysis Details
Assembly composition:
hetero undecamer (preferred)
PDBe Complex ID:
PDB-CPX-106293 (preferred)
Entry contents:
7 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (9 distinct):
DNA-directed RNA polymerase subunit alpha
Molecule details ›
Chains: A, B, T
Length: 350 amino acids
Theoretical weight: 37.96 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
Sequence domains:
Length: 350 amino acids
Theoretical weight: 37.96 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
- Canonical:
A0QSL8 (Residues: 1-350; Coverage: 100%)
Sequence domains:
- RNA polymerase Rpb3/Rpb11 dimerisation domain
- RNA polymerase Rpb3/RpoA insert domain
- Bacterial RNA polymerase, alpha chain C terminal domain
DNA-directed RNA polymerase subunit beta
Molecule details ›
Chain: C
Length: 1169 amino acids
Theoretical weight: 128.68 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
Sequence domains:
Length: 1169 amino acids
Theoretical weight: 128.68 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
- Canonical: P60281 (Residues: 1-1169; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase subunit beta'
DNA-directed RNA polymerase subunit omega
RNA polymerase sigma factor SigA
RNA polymerase-binding protein RbpA
