› 6cgs

X-ray diffraction
1.72Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183888 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadherin-7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 207 amino acids
Theoretical weight: 22.77 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8BM92 (Residues: 48-254; Coverage: 27%)
Gene name: Cdh7
Sequence domains: Cadherin domain
Structure domains: Cadherins

Ligands and Environments

2 bound ligands:
Ligand CA 6 x CA
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P212121
Unit cell:
a: 58.304Å b: 82.431Å c: 93.546Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.16 0.199
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Adhesion Protein Structure, Molecular Affinities, and Principles of Cell-Cell Recognition.
Honig et al. (2020)
4 more

1 mention without citation

Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior.
Brasch et al. (2018)