› 6cws

Solution NMR

The NMR solution structure of CCL28

Released:
DOI: 10.2210/pdb6cws/pdb
PDB entry 6cws coloured by chain, ensemble of 20 models, front view.
PDB entry 6cws coloured by chain, ensemble of 20 models, side view.
PDB entry 6cws coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The Solution Structure of CCL28 Reveals Structural Lability that Does Not Constrain Antifungal Activity.
Thomas MA, He J, Peterson FC, Huppler AR, Volkman BF
J Mol Biol 430 3266-3282 (2018)
PMID: 29913161

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192562 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 28 Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.39 KDa
Source organism: Homo sapiens
Expression system: Aphyosemion etsamense
UniProt:
  • Canonical: Q9NRJ3 (Residues: 20-127; Coverage: 100%)
Gene names: CCL28, SCYA28
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: torsion angle dynamics
Expression system: Aphyosemion etsamense

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Citations

1 review citation

Chemokine Heteromers and Their Impact on Cellular Function-A Conceptual Framework.
Blanchet et al. (2023)
5 other articles

6 mentions without citation

The marriage of chemokines and galectins as functional heterodimers.
von Hundelshausen et al. (2021)
5 more