Function and Biology

Crystal structure of Bothropstoxin I (BthTX-I) complexed to Chicoric acid

Source organism: Bothrops jararacussu
Biochemical function: toxin activity
Biological process: arachidonate secretion
Cellular component: extracellular region

Sequence family

Pfam Protein family (Pfam)
PF00068
Domain description: Phospholipase A2
Occurring in:
  1. Basic phospholipase A2 homolog bothropstoxin-I
The deposited structure of PDB entry 6dik contains 2 copies of Pfam domain PF00068 (Phospholipase A2) in Basic phospholipase A2 homolog bothropstoxin-I. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001211
Domain description: Phospholipase A2
Occurring in:
  1. Basic phospholipase A2 homolog bothropstoxin-I
IPR016090
Domain description: Phospholipase A2 domain
Occurring in:
  1. Basic phospholipase A2 homolog bothropstoxin-I
IPR036444
Domain description: Phospholipase A2 domain superfamily
Occurring in:
  1. Basic phospholipase A2 homolog bothropstoxin-I
IPR033112
Domain description: Phospholipase A2, aspartic acid active site
Occurring in:
  1. Basic phospholipase A2 homolog bothropstoxin-I
IPR033113
Domain description: Phospholipase A2, histidine active site
Occurring in:
  1. Basic phospholipase A2 homolog bothropstoxin-I

Structure domain

CATH CATH domain
1.20.90.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Phospholipase A2
Homology: Phospholipase A2 domain
Occurring in:
  1. Basic phospholipase A2 homolog bothropstoxin-I
The deposited structure of PDB entry 6dik contains 2 copies of CATH domain 1.20.90.10 (Phospholipase A2) in Basic phospholipase A2 homolog bothropstoxin-I. Showing 1 copy in chain A.