› 6dk4

X-ray diffraction
2.71Å resolution

Crystal structure of Campylobacter jejuni peroxide stress regulator

Released:
DOI: 10.2210/pdb6dk4/pdb
PDB entry 6dk4 coloured by chain, front view.
PDB entry 6dk4 coloured by chain, side view.
PDB entry 6dk4 coloured by chain, top view.
Source organism: Campylobacter jejuni
Primary publication:
Crystal structure of Campylobacter jejuni peroxide regulator.
Sarvan S, Charih F, Butcher J, Brunzelle JS, Stintzi A, Couture JF
FEBS Lett 592 2351-2360 (2018)
PMID: 29856899

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171056 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxide stress regulator Chains: A, B
Molecule details ›
Chains: A, B
Length: 142 amino acids
Theoretical weight: 16.75 KDa
Source organism: Campylobacter jejuni
Expression system: Escherichia coli
UniProt:
  • Canonical: Q0PBI7 (Residues: 1-136; Coverage: 100%)
Gene names: Cj0322, perR
Sequence domains: Ferric uptake regulator family

Ligands and Environments

3 bound ligands:
Ligand MN 2 x MN
Ligand ZN 2 x ZN
Ligand MPD 4 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 48.11Å b: 70.186Å c: 85.158Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.215 0.27
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Variation on a theme: investigating the structural repertoires used by ferric uptake regulators to control gene expression.
Sarvan et al. (2018)
1 more

3 mentions without citation

How Bacterial Redox Sensors Transmit Redox Signals via Structural Changes.
Lee et al. (2021)
2 more