6do3

X-ray diffraction
2.16Å resolution

KLHDC2 ubiquitin ligase in complex with SelK C-end degron

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-195167 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kelch domain-containing protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 363 amino acids
Theoretical weight: 41.35 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9Y2U9 (Residues: 1-362; Coverage: 89%)
Gene names: HCA33, KLHDC2
Sequence domains: Galactose oxidase, central domain
Selenoprotein K Chains: C, D
Molecule details ›
Chains: C, D
Length: 7 amino acids
Theoretical weight: 626 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9Y6D0 (Residues: 85-91; Coverage: 7%)
Gene names: HSPC030, HSPC297, SELENOK, SELK

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P21
Unit cell:
a: 44.816Å b: 87.779Å c: 88.626Å
α: 90° β: 104.49° γ: 90°
R-values:
R R work R free
0.169 0.166 0.223
Expression systems:
  • Trichoplusia ni
  • Not provided