Function and Biology

Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor

Source organisms:
Biochemical function: metal ion binding
Biological process: electron transport chain
Cellular component: periplasmic space

Sequence families

Pfam Protein families (Pfam)
PF07361
Domain description: Cytochrome b562
Occurring in:
  1. 5-hydroxytryptamine receptor 2B; Soluble cytochrome b562
The deposited structure of PDB entry 6dry contains 1 copy of Pfam domain PF07361 (Cytochrome b562) in 5-hydroxytryptamine receptor 2B. Showing 1 copy in chain A.

PF00001
Domain description: 7 transmembrane receptor (rhodopsin family)
Occurring in:
  1. 5-hydroxytryptamine receptor 2B; Soluble cytochrome b562
The deposited structure of PDB entry 6dry contains 1 copy of Pfam domain PF00001 (7 transmembrane receptor (rhodopsin family)) in 5-hydroxytryptamine receptor 2B. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000276
Domain description: G protein-coupled receptor, rhodopsin-like
Occurring in:
  1. 5-hydroxytryptamine receptor 2B; Soluble cytochrome b562
IPR002231
Domain description: 5-hydroxytryptamine receptor family
Occurring in:
  1. 5-hydroxytryptamine receptor 2B; Soluble cytochrome b562
IPR009155
Domain description: Cytochrome b562
Occurring in:
  1. 5-hydroxytryptamine receptor 2B; Soluble cytochrome b562
IPR010980
Domain description: Cytochrome c/b562
Occurring in:
  1. 5-hydroxytryptamine receptor 2B; Soluble cytochrome b562
IPR017452
Domain description: GPCR, rhodopsin-like, 7TM
Occurring in:
  1. 5-hydroxytryptamine receptor 2B; Soluble cytochrome b562