› 6dus

X-ray diffraction
2.6Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-494259 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type III secretion system effector arginine glycosyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 310 amino acids
Theoretical weight: 35.15 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3NMP8 (Residues: 26-335; Coverage: 93%)
Gene names: G1W50_07705, G1W53_11560, G1W54_11945, G1W56_12450, G1W63_12255, G1W64_12270, G1W86_10855, G1W87_22055, G1W89_11745, G1X03_12135, G1X09_12595, G1X10_12510, G1X13_12590, G1X15_07355, G1X17_12600, G1X23_12495, G1X32_11650, G1X38_11955, G1X47_10960, G1X49_12150, G1X51_12595, G1X66_11955, G1X68_11040, G1X69_12865, G1X71_12600, G1X76_11625, G1X80_11625, G1X84_19410, G1X85_22430, G1X86_11055, G1X94_11480, G1X96_11060, G1X99_12285, G1Y02_11655

Ligands and Environments

5 bound ligands:
Ligand UDP 2 x UDP
Ligand NAG 2 x NAG
Ligand MG 2 x MG
Ligand TRS 2 x TRS
Ligand MPD 2 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21212
Unit cell:
a: 96.49Å b: 107.12Å c: 74.73Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.178 0.225
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Salmonella Typhimurium and inflammation: a pathogen-centric affair.
Galán JE. (2021)
13 more

2 mentions without citation

Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways.
Newson et al. (2019)
1 more