› 6dvw

Electron Microscopy
4.3Å resolution

Cryo-EM structure of mouse TRPV3

Released:
DOI: 10.2210/pdb6dvw/pdb
PDB entry 6dvw coloured by chain, front view.
PDB entry 6dvw coloured by chain, side view.
PDB entry 6dvw coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure and gating mechanism of the transient receptor potential channel TRPV3.
Singh AK, McGoldrick LL, Sobolevsky AI
OpenAccess logo Nat Struct Mol Biol 25 805-813 (2018)
PMID: 30127359
Related structures: EMD-8919

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185081 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transient receptor potential cation channel subfamily V member 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 791 amino acids
Theoretical weight: 90.71 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8K424 (Residues: 1-1, 3-791; Coverage: 100%)
Gene name: Trpv3
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.3Å
Relevant EMDB volumes: EMD-8919
Expression system: Homo sapiens

Quick links

Citations

19 review citations

A structural overview of the ion channels of the TRPM family.
Huang et al. (2020)
18 more

18 mentions without citation

Structural insights into the gating mechanisms of TRPV channels.
Pumroy et al. (2020)
17 more