Function and Biology

SAMHD1 Bound to Clofarabine-TP in the Catalytic Pocket and Allosteric Pocket

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF01966
Domain description: HD domain
Occurring in:
  1. Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
The deposited structure of PDB entry 6dwd contains 4 copies of Pfam domain PF01966 (HD domain) in Deoxynucleoside triphosphate triphosphohydrolase SAMHD1. Showing 1 copy in chain C [auth B].

InterPro InterPro annotations
IPR006674
Domain description: HD domain
Occurring in:
  1. Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
IPR003607
Domain description: HD/PDEase domain
Occurring in:
  1. Deoxynucleoside triphosphate triphosphohydrolase SAMHD1