› 6dzc

Solution NMR

Solution structure of Rbfox2 RRM mimetic peptide CPfox6

Released:
DOI: 10.2210/pdb6dzc/pdb
PDB entry 6dzc coloured by chain, ensemble of 10 models, front view.
PDB entry 6dzc coloured by chain, ensemble of 10 models, side view.
PDB entry 6dzc coloured by chain, ensemble of 10 models, top view.
Source organism: Aspergillus fischeri
Primary publication:
A Small Cyclic β-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Sun YT, Shortridge MD, Varani G
Chembiochem 20 931-939 (2019)
PMID: 30537200

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166636 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CPfox6 Chain: A
Molecule details ›
Chain: A
Length: 16 amino acids
Theoretical weight: 1.94 KDa
Source organism: Aspergillus fischeri
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand DPR 1 x DPR

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 42%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

Small and Simple, yet Sturdy: Conformationally Constrained Peptides with Remarkable Properties.
Bozovičar et al. (2021)
1 more