› 6e5f

X-ray diffraction
1.37Å resolution

Crystal structure of LpqN involved in cell envelope biogenesis of Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb6e5f/pdb
PDB entry 6e5f coloured by chain, front view.
PDB entry 6e5f coloured by chain, side view.
PDB entry 6e5f coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
Structural and functional evidence that lipoprotein LpqN supports cell envelope biogenesis in Mycobacterium tuberculosis.
Melly GC, Stokas H, Dunaj JL, Hsu FF, Rajavel M, Su CC, Yu EW, Purdy GE
J Biol Chem 294 15711-15723 (2019)
PMID: 31471317

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129470 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lipoprotein LpqN Chain: A
Molecule details ›
Chain: A
Length: 228 amino acids
Theoretical weight: 23.7 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O53780 (Residues: 1-228; Coverage: 100%)
Gene names: Rv0583c, lpqN
Sequence domains: Probable lipoprotein LpqN

Ligands and Environments

1 bound ligand:
Ligand L6T 1 x L6T
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: I4
Unit cell:
a: 80.004Å b: 80.004Å c: 59.239Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.177 0.204
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

Transporters Involved in the Biogenesis and Functionalization of the Mycobacterial Cell Envelope.
Jackson et al. (2021)
1 more

3 mentions without citation

Structural and Functional Diversity of Resistance-Nodulation-Cell Division Transporters.
Klenotic et al. (2021)
2 more