6emj

X-ray diffraction
2.3Å resolution

FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery

Released:
Model geometry
Fit model/data
Source organism: Homo sapiens
Entry authors: Benz J, Weigand S, Dengl S, Schlothauer T, Auer J, Ehler A, Kettenberger H, Lorenz S, Hirschheydt T, Georges G

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-214040 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
fAB heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 227 amino acids
Theoretical weight: 24.57 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
fAb light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 214 amino acids
Theoretical weight: 23.55 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P1
Unit cell:
a: 51.48Å b: 73.869Å c: 76.92Å
α: 69.34° β: 78.05° γ: 70.2°
R-values:
R R work R free
0.168 0.165 0.211
Expression system: Homo sapiens