› 6etk

X-ray diffraction
0.85Å resolution

Atomic resolution structure of RNase A (data collection 1)

Released:
DOI: 10.2210/pdb6etk/pdb
PDB entry 6etk coloured by chain, front view.
PDB entry 6etk coloured by chain, side view.
PDB entry 6etk coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Raman-markers of X-ray radiation damage of proteins.
Vergara A, Caterino M, Merlino A
Int J Biol Macromol 111 1194-1205 (2018)
PMID: 29374529

Function and Biology Details

Reaction catalysed: 
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158390 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease pancreatic Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

1 bound ligand:
Ligand IPA 2 x IPA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 29.125Å b: 37.971Å c: 52.541Å
α: 90° β: 105.83° γ: 90°
R-values:
R R work R free
0.121 0.116 0.15

Quick links

Citations

1 review citation

Combining on-line spectroscopy with synchrotron and X-ray free electron laser crystallography.
Makita et al. (2023)
1 other article

3 mentions without citation

A base measure of precision for protein stability predictors: structural sensitivity.
Caldararu et al. (2021)
2 more