6f2x

Solution NMR

Structural characterization of the Mycobacterium tuberculosis Protein Tyrosine Kinase A (PtkA)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-161986 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase PtkA Chain: A
Molecule details ›
Chain: A
Length: 216 amino acids
Theoretical weight: 22.87 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WPI9 (Residues: 76-291; Coverage: 74%)
Gene names: MTCY427.13/MTCY427.14, Rv2232, ptkA
Sequence domains: Haloacid dehalogenase-like hydrolase
Structure domains: HAD superfamily/HAD-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 74%
Refinement method: simulated annealing with torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)