› 6f4u

X-ray diffraction
1.9Å resolution

Crystal structure of reactive loop cleaved kallistatin at 1.9 angstrom resolution

Released:
DOI: 10.2210/pdb6f4u/pdb
PDB entry 6f4u coloured by chain, front view.
PDB entry 6f4u coloured by chain, side view.
PDB entry 6f4u coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zhou A, Wei Z, Lin F

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-542012 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kallistatin Chain: A
Molecule details ›
Chain: A
Length: 341 amino acids
Theoretical weight: 39.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29622 (Residues: 48-387; Coverage: 84%)
Gene names: KST, PI4, SERPINA4
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Kallistatin Chain: D
Molecule details ›
Chain: D
Length: 40 amino acids
Theoretical weight: 4.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29622 (Residues: 388-427; Coverage: 10%)
Gene names: KST, PI4, SERPINA4

Ligands and Environments

4 bound ligands:
Ligand EDO 7 x EDO
Ligand GOL 2 x GOL
Ligand CL 1 x CL
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P61
Unit cell:
a: 113.51Å b: 113.51Å c: 76.172Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.195
Expression system: Escherichia coli BL21(DE3)

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