› 6f70

X-ray diffraction
1.48Å resolution

Crystal structure of glutathione transferase Omega 6S from Trametes versicolor

Released:
DOI: 10.2210/pdb6f70/pdb
PDB entry 6f70 coloured by chain, front view.
PDB entry 6f70 coloured by chain, side view.
PDB entry 6f70 coloured by chain, top view.
Source organism: Trametes versicolor
Primary publication:
Molecular recognition of wood polyphenols by phase II detoxification enzymes of the white rot Trametes versicolor.
Schwartz M, Perrot T, Aubert E, Dumarçay S, Favier F, Gérardin P, Morel-Rouhier M, Mulliert G, Saiag F, Didierjean C, Gelhaye E
OpenAccess logo Sci Rep 8 8472 (2018)
PMID: 29855494

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104739 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GST N-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 252 amino acids
Theoretical weight: 27.82 KDa
Source organism: Trametes versicolor
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A384E158 (Residues: 1-252; Coverage: 100%)
Sequence domains:

Ligands and Environments


Cofactor: Ligand GSH 1 x GSH
2 bound ligands:
Ligand GOL 1 x GOL
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P21
Unit cell:
a: 53.06Å b: 78.5Å c: 67.86Å
α: 90° β: 106.56° γ: 90°
R-values:
R R work R free
0.158 0.156 0.18
Expression system: Escherichia coli

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Citations

4 review citations

Modes-of-action of antifungal compounds: Stressors and (target-site-specific) toxins, toxicants, or toxin-stressors.
Noel et al. (2023)
3 more

1 mention without citation

Molecular recognition of wood polyphenols by phase II detoxification enzymes of the white rot Trametes versicolor.
Schwartz et al. (2018)