› 6ffr

Solution NMR

DNA-RNA Hybrid Quadruplex with Flipped Tetrad

Released:
DOI: 10.2210/pdb6ffr/pdb
PDB entry 6ffr coloured by chain, ensemble of 10 models, front view.
PDB entry 6ffr coloured by chain, ensemble of 10 models, side view.
PDB entry 6ffr coloured by chain, ensemble of 10 models, top view.
Source organism: synthetic construct
Primary publication:
DNA-RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies.
Haase L, Dickerhoff J, Weisz K
Chemistry 24 15365-15371 (2018)
PMID: 30084512

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113217 (preferred)
Entry contents:
1 distinct DNA/RNA hybrid molecule
Macromolecule:
DNA/RNA (5'-R(*G)-D(P*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*GP*AP*C)-R(P*G)-D(P*GP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 22 nucleotides
Theoretical weight: 7 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 36%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

1 review citation

Thermodynamic Stability of G-Quadruplexes: Impact of Sequence and Environment.
Jana et al. (2021)
3 other articles

1 mention without citation

ASC-G4, an algorithm to calculate advanced structural characteristics of G-quadruplexes.
Farag et al. (2023)