GO terms
Biochemical function:
- CCR chemokine receptor binding
- chemokine receptor antagonist activity
- protein homodimerization activity
- identical protein binding
- chemokine receptor binding
- chemoattractant activity
- CCR5 chemokine receptor binding
- CCR4 chemokine receptor binding
- CCR1 chemokine receptor binding
- receptor signaling protein tyrosine kinase activator activity
- phospholipase activator activity
- chemokine activity
- protein binding
- cytokine activity
- protein kinase activity
- phosphatidylinositol-4,5-bisphosphate phospholipase C activity
Biological process:
- positive regulation of natural killer cell chemotaxis
- positive regulation of T cell migration
- negative regulation of macrophage apoptotic process
- positive regulation of receptor signaling pathway via STAT
- cellular response to virus
- cell surface receptor signaling pathway via STAT
- positive regulation of monocyte chemotaxis
- cellular response to tumor necrosis factor
- cellular response to interleukin-1
- cellular response to type II interferon
- positive regulation of T cell apoptotic process
- negative regulation of T cell apoptotic process
- negative regulation of chemokine-mediated signaling pathway
- chemokine-mediated signaling pathway
- antimicrobial humoral immune response mediated by antimicrobial peptide
- positive regulation of calcium ion transport
- positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
- positive chemotaxis
- regulation of T cell activation
- regulation of insulin secretion
- positive regulation of epithelial cell proliferation
- epithelial cell proliferation
- positive regulation of smooth muscle cell proliferation
- macrophage chemotaxis
- eosinophil chemotaxis
- positive regulation of translational initiation
- positive regulation of cell adhesion
- positive regulation of G protein-coupled receptor signaling pathway
- negative regulation of G protein-coupled receptor signaling pathway
- positive regulation of innate immune response
- negative regulation of viral genome replication
- positive regulation of viral genome replication
- cellular response to fibroblast growth factor stimulus
- negative regulation by host of viral transcription
- neutrophil activation
- positive regulation of T cell proliferation
- chemokine (C-C motif) ligand 5 signaling pathway
- response to tumor necrosis factor
- positive regulation of homotypic cell-cell adhesion
- response to cytokine
- positive regulation of cell-cell adhesion mediated by integrin
- positive regulation of TOR signaling
- phospholipase D-activating G protein-coupled receptor signaling pathway
- positive regulation of cell migration
- positive regulation of smooth muscle cell migration
- positive regulation of T cell chemotaxis
- positive regulation of macrophage chemotaxis
- response to toxic substance
- response to virus
- cell-cell signaling
- G protein-coupled receptor signaling pathway
- leukocyte cell-cell adhesion
- immune response
- inflammatory response
- chemotaxis
- exocytosis
- intracellular calcium ion homeostasis
- calcium ion transport
- regulation of chronic inflammatory response
- monocyte chemotaxis
- dendritic cell chemotaxis
Protein family (Pfam)
InterPro annotations
CATH domain