Function and Biology

Crystal structure of N2C/D282C stabilized opsin bound to RS13

Source organism: Bos taurus
Biochemical function: arrestin family protein binding
Biological process: rod bipolar cell differentiation
Cellular component: sperm head plasma membrane

Sequence families

Pfam Protein families (Pfam)
PF00001
Domain description: 7 transmembrane receptor (rhodopsin family)
Occurring in:
  1. Rhodopsin
The deposited structure of PDB entry 6fkb contains 1 copy of Pfam domain PF00001 (7 transmembrane receptor (rhodopsin family)) in Rhodopsin. Showing 1 copy in chain A.

PF10413
Domain description: Amino terminal of the G-protein receptor rhodopsin
Occurring in:
  1. Rhodopsin
The deposited structure of PDB entry 6fkb contains 1 copy of Pfam domain PF10413 (Amino terminal of the G-protein receptor rhodopsin) in Rhodopsin. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000276
Domain description: G protein-coupled receptor, rhodopsin-like
Occurring in:
  1. Rhodopsin
IPR000732
Domain description: Rhodopsin
Occurring in:
  1. Rhodopsin
IPR001760
Domain description: Opsin
Occurring in:
  1. Rhodopsin
IPR027430
Domain description: Visual pigments (opsins) retinal binding site
Occurring in:
  1. Rhodopsin
IPR017452
Domain description: GPCR, rhodopsin-like, 7TM
Occurring in:
  1. Rhodopsin
IPR019477
Domain description: Rhodopsin, N-terminal
Occurring in:
  1. Rhodopsin

Structure domain

CATH CATH domain
1.20.1070.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Rhopdopsin 7-helix transmembrane proteins
Homology: Rhodopsin 7-helix transmembrane proteins
Occurring in:
  1. Rhodopsin
The deposited structure of PDB entry 6fkb contains 1 copy of CATH domain 1.20.1070.10 (Rhopdopsin 7-helix transmembrane proteins) in Rhodopsin. Showing 1 copy in chain A.