› 6fly

X-ray diffraction
2.75Å resolution

Structure of AcmJRL, a mannose binding jacalin related lectin from Ananas comosus, in complex with mannose.

Released:
DOI: 10.2210/pdb6fly/pdb
PDB entry 6fly coloured by chain, front view.
PDB entry 6fly coloured by chain, side view.
PDB entry 6fly coloured by chain, top view.
Source organism: Ananas comosus
Primary publication:
Biochemical and structural characterization of a mannose binding jacalin-related lectin with two-sugar binding sites from pineapple (Ananas comosus) stem.
Azarkan M, Feller G, Vandenameele J, Herman R, El Mahyaoui R, Sauvage E, Vanden Broeck A, Matagne A, Charlier P, Kerff F
OpenAccess logo Sci Rep 8 11508 (2018)
PMID: 30065388

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176110 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Jacalin-type lectin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 144 amino acids
Theoretical weight: 15.36 KDa
Source organism: Ananas comosus
UniProt:
  • Canonical: Q53J09 (Residues: 2-145; Coverage: 99%)
Gene name: LOC109719601
Sequence domains: Jacalin-like lectin domain
Structure domains: Jacalin-like lectin domain

Ligands and Environments

1 bound ligand:
Ligand MAN 4 x MAN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P6122
Unit cell:
a: 86.68Å b: 86.68Å c: 257.27Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.189 0.187 0.221

Quick links

Citations

1 review citation

Man-Specific Lectins from Plants, Fungi, Algae and Cyanobacteria, as Potential Blockers for SARS-CoV, MERS-CoV and SARS-CoV-2 (COVID-19) Coronaviruses: Biomedical Perspectives.
Barre et al. (2021)
6 other articles

2 mentions without citation

Biochemical and structural characterization of a mannose binding jacalin-related lectin with two-sugar binding sites from pineapple (Ananas comosus) stem.
Azarkan et al. (2018)
1 more