Function and Biology Details
Reaction catalysed:
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Superoxide dismutase, copper/zinc binding domain
- Superoxide dismutase-like, copper/zinc binding domain superfamily
- Heavy metal-associated domain, HMA
- Superoxide dismutase, copper/zinc, binding site
- Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone
- Heavy metal-associated domain superfamily
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127024 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Copper chaperone for superoxide dismutase
Molecule details ›
Chains: A, C
Length: 252 amino acids
Theoretical weight: 26.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 252 amino acids
Theoretical weight: 26.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
O14618 (Residues: 8-259; Coverage: 92%)
Sequence domains:
Superoxide dismutase [Cu-Zn]
Molecule details ›
Chains: B, D
Length: 153 amino acids
Theoretical weight: 15.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Length: 153 amino acids
Theoretical weight: 15.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P00441 (Residues: 2-154; Coverage: 99%)
Sequence domains: Copper/zinc superoxide dismutase (SODC)
