› 6fxa

X-ray diffraction
1.5Å resolution

Dimerization domain of TP901-1 CI repressor

Released:
DOI: 10.2210/pdb6fxa/pdb
PDB entry 6fxa coloured by chain, front view.
PDB entry 6fxa coloured by chain, side view.
PDB entry 6fxa coloured by chain, top view.
Source organism: Lactococcus phage TP901-1
Primary publication:
Structural basis of the bacteriophage TP901-1 CI repressor dimerization and interaction with DNA.
Rasmussen KK, Varming AK, Schmidt SN, Frandsen KEH, Thulstrup PW, Jensen MR, Lo Leggio L
FEBS Lett 592 1738-1750 (2018)
PMID: 29683476

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129243 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH cro/C1-type domain-containing protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 35 amino acids
Theoretical weight: 4.16 KDa
Source organism: Lactococcus phage TP901-1
Expression system: Not provided
UniProt:
  • Canonical: O48503 (Residues: 90-124; Coverage: 19%)
Gene name: cI

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, DESY BEAMLINE P11
Spacegroup: P212121
Unit cell:
a: 43.84Å b: 42.56Å c: 101.16Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.148 0.146 0.2
Expression system: Not provided

Quick links

Citations

2 citation in other articles

Repression of the lysogenic PR promoter in bacteriophage TP901-1 through binding of a CI-MOR complex to a composite OM-OR operator.
Pedersen et al. (2020)
1 more

1 mention without citation

Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition.
Beck et al. (2024)