› 6fzr

X-ray diffraction
1.8Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210666 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
scFv-SM3 Chain: H
Molecule details ›
Chain: H
Length: 244 amino acids
Theoretical weight: 25.76 KDa
Source organism: Mus musculus
Expression system: Komagataella pastoris
Structure domains: Immunoglobulins
Mucin-1 subunit alpha Chain: P
Molecule details ›
Chain: P
Length: 6 amino acids
Theoretical weight: 657 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P15941 (Residues: 921-926; Coverage: 1%)
Gene names: MUC1, PUM

Ligands and Environments

2 bound ligands:
Ligand EDO 8 x EDO
Ligand EEQ 1 x EEQ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P212121
Unit cell:
a: 35.274Å b: 69.431Å c: 90.778Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.187 0.232
Expression systems:
  • Komagataella pastoris
  • Not provided

Quick links

Citations

5 review citations

Oligosaccharide Synthesis and Translational Innovation.
Krasnova et al. (2019)
4 more

1 mention without citation

The effect of a methyl group on structure and function: Serine vs. threonine glycosylation and phosphorylation.
Barchi et al. (2023)