Function and Biology Details
Reactions catalysed:
Endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end-products
RNA = a 5'-hydroxy-ribonucleotide + n nucleoside-2',3'-cyclophosphates
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106192 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
1 distinct RNA molecule
2 distinct DNA molecules
1 distinct RNA molecule
Macromolecules (4 distinct):
CRISPR-associated endonuclease Cas12a
Molecule details ›
Chain: A
Length: 1329 amino acids
Theoretical weight: 155.64 KDa
Source organism: Francisella tularensis subsp. novicida U112
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Length: 1329 amino acids
Theoretical weight: 155.64 KDa
Source organism: Francisella tularensis subsp. novicida U112
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
A0Q7Q2 (Residues: 1-1300; Coverage: 100%)
Sequence domains:
