› 6gze

X-ray diffraction
2.49Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-237166 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Tubulin alpha-1B chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 440 amino acids
Theoretical weight: 48.97 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P81947 (Residues: 1-440; Coverage: 98%)
Sequence domains:
Tubulin beta-2B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 445 amino acids
Theoretical weight: 50 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q6B856 (Residues: 1-445; Coverage: 100%)
Gene name: TUBB2B
Sequence domains:
Stathmin-4 Chain: E
Tubulin tyrosine ligase Chain: F

Ligands and Environments

7 bound ligands:
Ligand GTP 2 x GTP
Ligand MG 5 x MG
Ligand CA 3 x CA
Ligand GDP 2 x GDP
Ligand MES 1 x MES
Ligand BEF 1 x BEF
Ligand ACP 1 x ACP
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 104.176Å b: 156.744Å c: 180.587Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.212 0.256
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Regulation of microtubule dynamics, mechanics and function through the growing tip.
Gudimchuk et al. (2021)
5 more

2 mentions without citation

Structural model for differential cap maturation at growing microtubule ends.
Estévez-Gallego et al. (2020)
1 more

PDB-REDO

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