› 6h6l

X-ray diffraction
2.5Å resolution

Murine norovirus protruding domain (CW3 strain) in complex with the CD300lf receptor and glycochenodeoxycholate (GCDCA)

Released:
DOI: 10.2210/pdb6h6l/pdb
PDB entry 6h6l coloured by chain, front view.
PDB entry 6h6l coloured by chain, side view.
PDB entry 6h6l coloured by chain, top view.
Source organisms:
Entry authors: Kilic T, Hansman GS

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108404 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Capsid protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 303 amino acids
Theoretical weight: 33.06 KDa
Source organism: Murine norovirus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A7U694 (Residues: 228-530; Coverage: 56%)
Sequence domains: Calicivirus coat protein C-terminal
CMRF35-like molecule 1 Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 112 amino acids
Theoretical weight: 12.66 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6SJQ7 (Residues: 20-128; Coverage: 34%)
  • Best match: Q6SJQ7-2 (Residues: 20-131)
Gene names: Cd300lf, Clm1, Lmir3
Sequence domains: Immunoglobulin V-set domain

Ligands and Environments

4 bound ligands:
Ligand MG 8 x MG
Ligand CHO 4 x CHO
Ligand NA 4 x NA
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P41
Unit cell:
a: 87Å b: 87Å c: 276.81Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.189 0.216
Expression systems:
  • Escherichia coli BL21(DE3)
  • Escherichia coli

Quick links