Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104323 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Golgi resident protein GCP60, N-terminally processed
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 19.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Golgi-dynamics membrane-trafficking
Length: 168 amino acids
Theoretical weight: 19.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9H3P7 (Residues: 364-528; Coverage: 31%)
Sequence domains: Golgi-dynamics membrane-trafficking
Genome polyprotein
Molecule details ›
Chain: B
Length: 50 amino acids
Theoretical weight: 5.51 KDa
Source organism: enterovirus D68
Expression system: Escherichia coli BL21(DE3)
UniProt:
Length: 50 amino acids
Theoretical weight: 5.51 KDa
Source organism: enterovirus D68
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: A0A2K9Y515 (Residues: 1454-1498; Coverage: 2%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
BESSY BEAMLINE 14.1
Spacegroup:
C2
Expression system: Escherichia coli BL21(DE3)
