6huv

X-ray diffraction
3.1Å resolution

Yeast 20S proteasome with human beta2c (S171G) in complex with 39

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 28-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149190 (preferred)
Entry contents:
14 distinct polypeptide molecules
Macromolecules (14 distinct):
Proteasome subunit alpha type-2 Chains: A, O
Molecule details ›
Chains: A, O
Length: 250 amino acids
Theoretical weight: 27.19 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P23639 (Residues: 1-250; Coverage: 100%)
Gene names: PRE8, PRS4, YML092C
Sequence domains:
Structure domains: Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Proteasome subunit alpha type-3 Chains: B, P
Molecule details ›
Chains: B, P
Length: 258 amino acids
Theoretical weight: 28.75 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P23638 (Residues: 1-258; Coverage: 100%)
Gene names: PRE9, PRS5, YGR135W
Sequence domains:
Structure domains: Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Proteasome subunit alpha type-4 Chains: C, Q
Proteasome subunit alpha type-5 Chains: D, R
Proteasome subunit alpha type-6 Chains: E, S
Probable proteasome subunit alpha type-7 Chains: F, T
Proteasome subunit alpha type-1 Chains: G, U
Proteasome subunit beta type-7 Chains: H, V
Proteasome subunit beta type-3 Chains: I, W
Proteasome subunit beta type-4 Chains: J, X
Proteasome subunit beta type-5 Chains: K, Y
Proteasome subunit beta type-6 Chains: L, Z
Proteasome subunit beta type-7 Chains: M, a
Proteasome subunit beta type-1 Chains: N, b

Ligands and Environments

No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 134.14Å b: 299.85Å c: 143.47Å
α: 90° β: 112.68° γ: 90°
R-values:
R R work R free
0.171 0.168 0.213
Expression system: Saccharomyces cerevisiae