Function and Biology Details
Reaction catalysed:
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Phosphatidylinositol 3-/4-kinase, catalytic domain
- Phosphoinositide 3-kinase, accessory (PIK) domain
- Phosphatidylinositol 3/4-kinase, conserved site
- Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily
- Protein kinase-like domain superfamily
- Phosphoinositide 3-kinase, accessory (PIK) domain superfamily
- Phosphatidylinositol kinase
- Armadillo-type fold
1 more domain
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-569532 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3-kinase catalytic subunit type 3
Molecule details ›
Chain: A
Length: 615 amino acids
Theoretical weight: 70.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 615 amino acids
Theoretical weight: 70.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8NEB9 (Residues: 268-686, 687-879; Coverage: 69%)
Sequence domains:
