Function and Biology Details
Reaction catalysed:
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
Assembly name:
Dipeptidyl peptidase 1 exclusion domain chain (preferred)
PDBe Complex ID:
PDB-CPX-156846 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Dipeptidyl peptidase 1 exclusion domain chain
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.5 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Cathepsin C exclusion domain
Structure domains: Cathepsin C, exclusion domain
Length: 119 amino acids
Theoretical weight: 13.5 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P53634 (Residues: 25-143; Coverage: 27%)
Sequence domains: Cathepsin C exclusion domain
Structure domains: Cathepsin C, exclusion domain
Dipeptidyl peptidase 1 heavy chain
Molecule details ›
Chain: B
Length: 162 amino acids
Theoretical weight: 18.3 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases
Length: 162 amino acids
Theoretical weight: 18.3 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P53634 (Residues: 230-391; Coverage: 37%)
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases
Dipeptidyl peptidase 1 light chain
Ligands and Environments
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
BRUKER X8 PROTEUM
Spacegroup:
I222
Expression system: Trichoplusia ni
